What the FDA labels say about taking them together
Itraconazole and quinine
Itraconazole's FDA label of July 13, 2026 names quinine in its drug interactions section; the quinine label PlainMeds reads does not name itraconazole. The itraconazole label: “Concomitant drug dose reduction may be necessary. Artemether-lumefantrine Quinine Monitor for adverse reactions.”
Check it at the source: the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.); the quinine FDA label on DailyMed (effective November 9, 2023).
What does the itraconazole label say about quinine?
Itraconazole label, drug interactionsConcomitant drug dose reduction may be necessary. Artemether-lumefantrine Quinine Monitor for adverse reactions.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
What does the quinine label say about itraconazole?
Quinine's label (effective November 9, 2023) does not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Chininum sulphuricum), Boiron, effective November 9, 2023 (SPL set 33885950-2a55-11e7-8288-424c58303031), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Itraconazole | Quinine | |
|---|---|---|
| Labeled for | Fungal infections | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.910 per capsule 100 mg capsule | $0.698 per capsule 324 mg capsule |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once