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What the FDA labels say about taking them together

Itraconazole and nadolol

Itraconazole's FDA label of July 13, 2026 names nadolol in its drug interactions section; the nadolol label PlainMeds reads does not name itraconazole. The itraconazole label: “… Tenofovir disoproxil fumarate Monitor for adverse reactions. Beta Blockers Nadolol Monitor for adverse reactions.”

Check it at the source: the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.); the nadolol FDA label on DailyMed (effective May 12, 2026, Amneal Pharmaceuticals NY LLC).

What does the itraconazole label say about nadolol?

Itraconazole label, drug interactions

Elbasvir/grazoprevir Not recommended during and 2 weeks after SPORANOX ® treatment. Glecaprevir/pibrentasvir Monitor for adverse reactions. Tenofovir disoproxil fumarate Monitor for adverse reactions. Beta Blockers Nadolol Monitor for adverse reactions.

Tolsura label (Mayne Pharma Commercial LLC, April 23, 2025), drug interactions

See also Table 5 . Tenofovir disoproxil fumarate Monitor for adverse reactions. Beta Blockers Nadolol Monitor for adverse reactions.

Source: FDA drug label (Tolsura, NDA208901), Mayne Pharma Commercial LLC, effective April 23, 2025 (SPL set 306352d1-9d5a-49ad-b72d-893b99546861), via openFDA

Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed

What does the nadolol label say about itraconazole?

Nadolol's label (effective May 12, 2026) does not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nadolol), Amneal Pharmaceuticals NY LLC, effective May 12, 2026 (SPL set e2e24b14-0169-4028-828a-894ad3c2ba55), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

11Itraconazole generic labelers
16Nadolol generic labelers
ItraconazoleNadolol
Labeled forFungal infectionsAngina, High blood pressure
Boxed warningYesNo
Pharmacy cost (NADAC)$0.910 per capsule 100 mg capsule$0.147 per tablet 20 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?