What the FDA labels say about taking them together
Itraconazole and mavacamten
Itraconazole's FDA label of July 13, 2026 names mavacamten in its drug interactions section; the mavacamten label PlainMeds reads does not name itraconazole. The itraconazole label: “Cardiac Myosin Inhibitor Mavacamten Refer to the mavacamten prescribing information for detailed guidance including dosing and safety monitoring.”
Check it at the source: the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.); the mavacamten FDA label on DailyMed (effective April 17, 2025, Myokardia, Inc.).
What does the itraconazole label say about mavacamten?
Itraconazole label, drug interactionsCardiac Myosin Inhibitor Mavacamten Refer to the mavacamten prescribing information for detailed guidance including dosing and safety monitoring.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
What does the mavacamten label say about itraconazole?
Mavacamten's label (effective April 17, 2025) does not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CAMZYOS), NDA214998 (Bristol), as published by Myokardia, Inc., effective April 17, 2025 (SPL set 669c936b-3ee6-4e36-8a22-79dd11b1255b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Itraconazole | Mavacamten | |
|---|---|---|
| Labeled for | Fungal infections | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.910 per capsule 100 mg capsule | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once