What the FDA labels say about taking them together
Cariprazine and itraconazole
Itraconazole's FDA label of July 13, 2026 names cariprazine in its drug interactions section; the cariprazine label PlainMeds reads does not name itraconazole. The itraconazole label: “Antipsychotics, Anxiolytics and Hypnotics Alprazolam Aripiprazole Buspirone Cariprazine Diazepam Haloperidol Midazolam (IV) Quetiapine Ramelteon Risperidone Suvorexant Monitor for adverse reactions.”
Check it at the source: the cariprazine FDA label on DailyMed (effective December 18, 2025, Allergan, Inc.); the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.).
What does the cariprazine label say about itraconazole?
Cariprazine's label (effective December 18, 2025) does not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Vraylar), NDA204370 (Abbvie), as published by Allergan, Inc., effective December 18, 2025 (SPL set 4b5f7c65-aa2d-452a-b3db-bc85c06ff12f), via openFDA; the full label on DailyMed
What does the itraconazole label say about cariprazine?
Itraconazole label, drug interactionsAntipsychotics, Anxiolytics and Hypnotics Alprazolam Aripiprazole Buspirone Cariprazine Diazepam Haloperidol Midazolam (IV) Quetiapine Ramelteon Risperidone Suvorexant Monitor for adverse reactions.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cariprazine | Itraconazole | |
|---|---|---|
| Labeled for | Schizophrenia, Bipolar disorder, Depression | Fungal infections |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $50.84 per capsule 1.5 mg capsule | $0.910 per capsule 100 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once