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What the FDA labels say about taking them together

Isavuconazonium and vincristine

Isavuconazonium's FDA label of April 25, 2025 names vincristine in its drug interactions section; the vincristine label PlainMeds reads does not name isavuconazonium. The isavuconazonium label: “Vincristine Avoid Concomitant Use Avoid concomitant use with CRESEMBA in pediatric and adult patients.”

Check it at the source: the isavuconazonium FDA label on DailyMed (effective April 25, 2025, Astellas Pharma US, Inc.); the vincristine FDA label on DailyMed (effective February 17, 2026, Hospira, Inc.).

What does the isavuconazonium label say about vincristine?

Isavuconazonium label, drug interactions

Vincristine Avoid Concomitant Use Avoid concomitant use with CRESEMBA in pediatric and adult patients.

Source: FDA drug label (CRESEMBA), Astellas Pharma US, Inc., effective April 25, 2025 (SPL set 8f7f73b8-586a-4df0-935f-fecd4696c16c), via openFDA; the full label on DailyMed

What does the vincristine label say about isavuconazonium?

Vincristine's label (effective February 17, 2026) does not name isavuconazonium in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (VinCRIStine Sulfate), Hospira, Inc., effective February 17, 2026 (SPL set b22e4c8e-dbe1-4d4b-a026-e1812974071c), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Isavuconazonium generic labelers
1Vincristine generic labelers
IsavuconazoniumVincristine
Labeled forn/aLeukemia, lymphoma and myeloma
Boxed warningNoYes
Pharmacy cost (NADAC)$114.00 per capsule 186 mg capsulen/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?