What the FDA labels say about taking them together
Isatuximab and lenalidomide
Isatuximab's FDA label of July 7, 2026 names lenalidomide in its warnings and precautions section; the lenalidomide label PlainMeds reads does not name isatuximab. The isatuximab label: “The combination of SARCLISA with pomalidomide or lenalidomide is contraindicated in pregnant women because pomalidomide or lenalidomide may cause birth defects and death of the unborn child.”
Check it at the source: the isatuximab FDA label on DailyMed (effective July 7, 2026); the lenalidomide FDA label on DailyMed (effective March 24, 2023, Celgene Corporation).
What does the isatuximab label say about lenalidomide?
Isatuximab label, warnings and precautionsThe combination of SARCLISA with pomalidomide or lenalidomide is contraindicated in pregnant women because pomalidomide or lenalidomide may cause birth defects and death of the unborn child.
Source: FDA drug label (Sarclisa Escena, BLA761445), Sanofi-Aventis U.S. LLC, effective July 10, 2026 (SPL set 07730e8c-1340-4d30-8d71-e20f850db8da), via openFDA
Source: FDA drug label (Sarclisa), Sanofi-Aventis U.S. LLC, effective July 7, 2026 (SPL set a0473462-6f9d-4eca-a5bf-8620aea68e8a), via openFDA; the full label on DailyMed
What does the lenalidomide label say about isatuximab?
Lenalidomide's label (effective March 24, 2023) does not name isatuximab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Revlimid), NDA021880 (Bristol Myers Squibb), as published by Celgene Corporation, effective March 24, 2023 (SPL set 5fa97bf5-28a2-48f1-8955-f56012d296be), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Isatuximab | Lenalidomide | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Leukemia, lymphoma and myeloma, Anemia |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once