What the FDA labels say about taking them together
Iptacopan and rifampin
Iptacopan's FDA label of July 16, 2026 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name iptacopan. The iptacopan label: “DRUG INTERACTIONS CYP2C8 inducers (e.g., rifampin): May decrease iptacopan exposure.”
Check it at the source: the iptacopan FDA label on DailyMed (effective July 16, 2026, Novartis Pharmaceuticals Corporation); the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.).
What does the iptacopan label say about rifampin?
Iptacopan label, drug interactionsDRUG INTERACTIONS CYP2C8 inducers (e.g., rifampin): May decrease iptacopan exposure.
Source: FDA drug label (FABHALTA), Novartis Pharmaceuticals Corporation, effective July 16, 2026 (SPL set a76b5845-6e21-4d3b-ad07-cd8df1b60bee), via openFDA; the full label on DailyMed
What does the rifampin label say about iptacopan?
Rifampin's label (effective February 11, 2026) does not name iptacopan in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Iptacopan | Rifampin | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.679 per capsule 300 mg capsule |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once