Skip to main content

What the FDA labels say about taking them together

Iohexol and metformin

Iohexol's FDA label of April 7, 2026 names metformin in its drug interactions section; the metformin labels PlainMeds reads (3) do not name iohexol.

Check it at the source: the iohexol FDA label on DailyMed (effective April 7, 2026, GE Healthcare Inc.); the metformin FDA label on DailyMed (effective September 3, 2026, Granules India Ltd).

What does the iohexol label say about metformin?

Iohexol label, drug interactions

DRUG INTERACTIONS 7.1 Drug-Drug Interactions Metformin In patients with renal impairment, metformin can cause lactic acidosis.

Source: FDA drug label (OMNIPAQUE), GE Healthcare Inc., effective April 7, 2026 (SPL set eee15ebe-d349-4497-acef-6abe7a8247fb), via openFDA; the full label on DailyMed

What does the metformin label say about iohexol?

Metformin's label (effective September 3, 2026) and its 2 other brand-application labels do not name iohexol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (METFORMIN HYDROCHLORIDE), Granules India Ltd, effective September 3, 2026 (SPL set 73197cb5-3e23-4ac0-b189-f9bc848bce66), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Iohexol generic labelers
80Metformin generic labelers
IohexolMetformin
Labeled forn/aType 2 diabetes
Boxed warningYesYes
Pharmacy cost (NADAC)n/a$0.0145 per tablet 500 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?