What the FDA labels say about taking them together
Insulin human and somatropin
Insulin human's FDA label of March 7, 2025 names somatropin in its drug interactions section; the somatropin labels PlainMeds reads (4) do not name insulin human. The insulin human label: “… niacin, oral contraceptives, phenothiazines, progestogens, protease inhibitors, somatropin, sympathomimetic agents, and thyroid hormones. …”
Check it at the source: the insulin human FDA label on DailyMed (effective March 7, 2025, Baxter Healthcare Corporation); the somatropin FDA label on DailyMed (effective August 20, 2026, Eli Lilly and Company).
What does the insulin human label say about somatropin?
Insulin human label, drug interactionsDrugs that May Decrease the Blood Glucose Lowering Effect of MYXREDLIN Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. Intervention: Dose adjustment and increased frequency of glucose monitoring may be required when MYXREDLIN is co-administered with these drugs.
Source: FDA drug label (Afrezza, BLA022472), Mannkind Corporation, effective May 30, 2026 (SPL set 29f4637b-e204-425b-b89c-7238008d8c10), via openFDA
Source: FDA drug label (Humulin R U-500 Kwikpen, BLA018780), Eli Lilly and Company, effective July 1, 2026 (SPL set b60e8dd0-1d48-4dc9-87fd-e14675255e8c), via openFDA
Source: FDA drug label (MYXREDLIN), Baxter Healthcare Corporation, effective March 7, 2025 (SPL set afca6e80-a802-49fb-a978-5fe28a173001), via openFDA; the full label on DailyMed
What does the somatropin label say about insulin human?
Somatropin's label (effective August 20, 2026) and its 3 other brand-application labels do not name insulin human in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (HUMATROPE), Eli Lilly and Company, effective August 20, 2026 (SPL set a774e1ae-3997-49ee-8b0e-99a2b315d409), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Insulin human | Somatropin | |
|---|---|---|
| Labeled for | Type 2 diabetes, Type 1 diabetes | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $4.26 per mL 70-30 vial | $752.22 per cartridge 5 mg cartridge |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once