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What the FDA labels say about taking them together

Insulin detemir and terbutaline

Insulin detemir's FDA label of October 9, 2024 names terbutaline in its drug interactions section; the terbutaline label PlainMeds reads does not name insulin detemir. The insulin detemir label: “Drugs That May Decrease the Blood Glucose Lowering Effect of LEVEMIR Drugs: Atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines …”

Check it at the source: the insulin detemir FDA label on DailyMed (effective October 9, 2024); the terbutaline FDA label on DailyMed (effective November 15, 2019, ANI Pharmaceuticals, Inc.).

What does the insulin detemir label say about terbutaline?

Insulin detemir label, drug interactions

Drugs That May Decrease the Blood Glucose Lowering Effect of LEVEMIR Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. Intervention: Dosage increases and increased frequency of glucose monitoring may be required when LEVEMIR is co-administered with these drugs.

Source: FDA drug label (Levemir), A-S Medication Solutions, effective October 9, 2024 (SPL set 82192527-99aa-4b53-8ce9-9173668d309c), via openFDA; the full label on DailyMed

What does the terbutaline label say about insulin detemir?

Terbutaline's label (effective November 15, 2019) does not name insulin detemir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Terbutaline Sulfate), NDA017849 (Ani Pharms), as published by ANI Pharmaceuticals, Inc., effective November 15, 2019 (SPL set d810a15b-3e10-4f6c-a36e-8ddecbaba9c3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Insulin detemir generic labelers
9Terbutaline generic labelers
Insulin detemirTerbutaline
Labeled forType 2 diabetes, Type 1 diabetesn/a
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.947 per tablet 2.5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?