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What the FDA labels say about taking them together

Clonidine and insulin detemir

Insulin detemir's FDA label of October 9, 2024 names clonidine in its drug interactions section; the clonidine labels PlainMeds reads (4) do not name insulin detemir. The insulin detemir label: “Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of LEVEMIR Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.”

Check it at the source: the clonidine FDA label on DailyMed (effective March 30, 2026, Unichem Pharmaceuticals (USA), Inc.); the insulin detemir FDA label on DailyMed (effective October 9, 2024).

What does the clonidine label say about insulin detemir?

Clonidine's label (effective March 30, 2026) and its 3 other brand-application labels do not name insulin detemir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (clonidine hydrochloride), Unichem Pharmaceuticals (USA), Inc., effective March 30, 2026 (SPL set 21bfa28f-20df-43fd-bb80-b720d3b40696), via openFDA; the full label on DailyMed

What does the insulin detemir label say about clonidine?

Insulin detemir label, drug interactions

Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of LEVEMIR Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.

Source: FDA drug label (Levemir), A-S Medication Solutions, effective October 9, 2024 (SPL set 82192527-99aa-4b53-8ce9-9173668d309c), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

43Clonidine generic labelers
0Insulin detemir generic labelers
ClonidineInsulin detemir
Labeled forHigh blood pressure, ADHD, PainType 2 diabetes, Type 1 diabetes
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0241 per tablet 0.1 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?