What the FDA labels say about taking them together
Infliximab and theophylline
Infliximab's FDA label of August 28, 2026 names theophylline in its drug interactions section; the theophylline label PlainMeds reads does not name infliximab. The infliximab label: “Upon initiation or discontinuation of AVSOLA in patients being treated with CYP450 substrates with a narrow therapeutic index, monitoring of the effect (e.g., warfarin) or drug concentration is recommended and the …”
Check it at the source: the infliximab FDA label on DailyMed (effective August 28, 2026); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the infliximab label say about theophylline?
Infliximab label, drug interactionsUpon initiation or discontinuation of RENFLEXIS in patients being treated with CYP450 substrates with a narrow therapeutic index, monitoring of the effect (e.g., warfarin) or drug concentration (e.g., cyclosporine or theophylline) is recommended and the individual dose of the drug product may be adjusted as needed.
Source: FDA drug label (Inflectra, BLA125544), Pfizer Laboratories Div Pfizer Inc, effective July 28, 2026 (SPL set 37eaca10-d812-48bc-8b8e-b836bfa9968f), via openFDA
Source: FDA drug label (Avsola, BLA761086), Amgen, Inc, effective July 22, 2026 (SPL set de34bcb7-b524-45c8-9181-61c6f48d540e), via openFDA
Source: FDA drug label (Infliximab, BLA103772), Janssen Biotech, Inc., effective February 11, 2026 (SPL set b05c174f-832c-4321-b34f-2c4ad3742269), via openFDA
Source: FDA drug label (Renflexis), Organon LLC, effective August 28, 2026 (SPL set dbf738c4-3fac-4422-a9d8-51d9c83a8789), via openFDA; the full label on DailyMed
What does the theophylline label say about infliximab?
Theophylline's label (effective March 10, 2026) does not name infliximab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Infliximab | Theophylline | |
|---|---|---|
| Labeled for | Rheumatoid arthritis, Crohn's disease and ulcerative colitis | Asthma |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once