Imipenem/Cilastatin and Ganciclovir Interaction
Drug interaction information between Imipenem/Cilastatin and Ganciclovir.
Imipenem/Cilastatin and Ganciclovir have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Imipenem/Cilastatin and Ganciclovir. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Using these two drugs at the same time can increase the chance of having a seizure.
FDA Label Information
7 DRUG INTERACTIONS Ganciclovir: Generalized seizures have been reported in patients who received ganciclovir. 7.1 Ganciclovir Generalized seizures have been reported in patients who received ganciclovir and PRIMAXIN.
Imipenem/Cilastatin Also Interacts With
- Probenecid moderate
Ganciclovir Also Interacts With
- Cyclosporine moderate
- Amphotericin B moderate
- Trimethoprim minor
- Probenecid minor
- Bictegravir/Emtricitabine/Tenofovir minor
Frequently Asked Questions
What SPL severity band is on file for Imipenem/Cilastatin + Ganciclovir?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Ganciclovir has 9 labeled pairs on file vs Imipenem/Cilastatin's 2. In the minor band specifically: Imipenem/Cilastatin has 1; Ganciclovir has 7 (also Trimethoprim, Probenecid, Bictegravir, Emtricitabine/Tenofovir).
What mechanism field is on file for Imipenem/Cilastatin and Ganciclovir?
Using these two drugs at the same time can increase the chance of having a seizure.
Ganciclovir's labeled portfolio outnumbers Imipenem/Cilastatin
SPL source-record counts only. This page's band is minor · classes on file: Imipenem/Cilastatin (Carbapenem Antibiotic Combination); Ganciclovir (Antiviral (Nucleoside Analog)).
0 major · 1 moderate · 1 minor · 2 total
Imipenem/Cilastatin has no other minor-band peer in this dataset besides Ganciclovir.
0 major · 2 moderate · 7 minor · 9 total
- Other minor peers for Ganciclovir
- Trimethoprim
- Probenecid
- Bictegravir
- Emtricitabine/Tenofovir
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.