What the FDA labels say about taking them together
Imatinib and tafamidis
Tafamidis's FDA label of May 12, 2026 names imatinib in its drug interactions section; the imatinib labels PlainMeds reads (3) do not name tafamidis. The tafamidis label: “Coadministration of tafamidis and drugs that are BCRP substrates may increase the exposure of substrates of this transporter and the risk of the substrate-related toxicities.”
Check it at the source: the imatinib FDA label on DailyMed (effective September 8, 2026, Apotex Corp); the tafamidis FDA label on DailyMed (effective May 12, 2026, Pfizer Laboratories Div Pfizer Inc).
What does the imatinib label say about tafamidis?
Imatinib's label (effective September 8, 2026) and its 2 other brand-application labels do not name tafamidis in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Imatinib Mesylate), Apotex Corp, effective September 8, 2026 (SPL set 0291eca5-7a1d-4a79-30be-252224d96509), via openFDA; the full label on DailyMed
What does the tafamidis label say about imatinib?
Tafamidis label, drug interactionsCoadministration of tafamidis and drugs that are BCRP substrates may increase the exposure of substrates of this transporter (e.g., methotrexate, rosuvastatin, imatinib) and the risk of the substrate-related toxicities.
Source: FDA drug label (Vyndaqel), NDA211996 (Foldrx Pharms), as published by Pfizer Laboratories Div Pfizer Inc, effective May 12, 2026 (SPL set 1b4121ee-a733-4456-a917-be2603477839), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Imatinib | Tafamidis | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.624 per tablet 100 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once