What the FDA labels say about taking them together
Imatinib and sofosbuvir/velpatasvir/voxilaprevir
Sofosbuvir/velpatasvir/voxilaprevir's FDA label of July 14, 2025 names imatinib in its drug interactions section; the imatinib labels PlainMeds reads (3) do not name sofosbuvir/velpatasvir/voxilaprevir. The sofosbuvir/velpatasvir/voxilaprevir label: “Coadministration of VOSEVI with BCRP substrates is not recommended.”
Check it at the source: the imatinib FDA label on DailyMed (effective September 8, 2026, Apotex Corp); the sofosbuvir/velpatasvir/voxilaprevir FDA label on DailyMed (effective July 14, 2025, Gilead Sciences, Inc.).
What does the imatinib label say about sofosbuvir/velpatasvir/voxilaprevir?
Imatinib's label (effective September 8, 2026) and its 2 other brand-application labels do not name sofosbuvir/velpatasvir/voxilaprevir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Imatinib Mesylate), Apotex Corp, effective September 8, 2026 (SPL set 0291eca5-7a1d-4a79-30be-252224d96509), via openFDA; the full label on DailyMed
What does the sofosbuvir/velpatasvir/voxilaprevir label say about imatinib?
Sofosbuvir/velpatasvir/voxilaprevir label, drug interactionsCoadministration of VOSEVI with BCRP substrates (e.g., methotrexate, mitoxantrone, imatinib, irinotecan, lapatinib, rosuvastatin, sulfasalazine, topotecan) is not recommended [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Vosevi), Gilead Sciences, Inc., effective July 14, 2025 (SPL set 17ffc094-8ca7-45d2-80d8-fd043bc9a221), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Imatinib | Sofosbuvir/velpatasvir/voxilaprevir | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Hepatitis C |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.624 per tablet 100 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once