What the FDA labels say about taking them together
Hydroxychloroquine and praziquantel
Hydroxychloroquine's FDA label of October 8, 2024 names praziquantel in its drug interactions section; the praziquantel label PlainMeds reads does not name hydroxychloroquine. The hydroxychloroquine label: “Chloroquine has been reported to reduce the bioavailability of praziquantel.”
Check it at the source: the hydroxychloroquine FDA label on DailyMed (effective October 8, 2024, ANI Pharmaceuticals, Inc.); the praziquantel FDA label on DailyMed (effective March 2, 2026, Bayer HealthCare Pharmaceuticals Inc.).
What does the hydroxychloroquine label say about praziquantel?
Hydroxychloroquine label, drug interactionsChloroquine has been reported to reduce the bioavailability of praziquantel.
Source: FDA drug label (SOVUNA), ANI Pharmaceuticals, Inc., effective October 8, 2024 (SPL set dd441154-b196-4d4c-bc56-2e37f345ef8d), via openFDA; the full label on DailyMed
What does the praziquantel label say about hydroxychloroquine?
Praziquantel's label (effective March 2, 2026) does not name hydroxychloroquine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Biltricide), Bayer HealthCare Pharmaceuticals Inc., effective March 2, 2026 (SPL set 34ce1cdd-648e-4f1e-8512-bf3d4cc22eb9), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Hydroxychloroquine | Praziquantel | |
|---|---|---|
| Labeled for | Rheumatoid arthritis | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.149 per tablet 200 mg tablet | $53.25 per tablet 600 mg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once