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What the FDA labels say about taking them together

Histamine and terbutaline

Histamine's FDA label of November 3, 2025 names terbutaline in its drug interactions (prescription label) section; the terbutaline label PlainMeds reads does not name histamine. The histamine label: “Beta 2 Agonists: Oral terbutaline and parenteral ephedrine, in general, have been shown to decrease allergen induced wheal.”

Check it at the source: the histamine FDA label on DailyMed (effective November 3, 2025); the terbutaline FDA label on DailyMed (effective November 15, 2019, ANI Pharmaceuticals, Inc.).

What does the histamine label say about terbutaline?

Histamine label, drug interactions (prescription label)

Beta 2 Agonists: Oral terbutaline and parenteral ephedrine, in general, have been shown to decrease allergen induced wheal.

Source: FDA drug label (Histaminum hydrochloricum), Boiron, effective November 3, 2025 (SPL set 85b905d4-5fa3-7125-e053-2a91aa0a54f4), via openFDA; the full label on DailyMed

What does the terbutaline label say about histamine?

Terbutaline's label (effective November 15, 2019) does not name histamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Terbutaline Sulfate), NDA017849 (Ani Pharms), as published by ANI Pharmaceuticals, Inc., effective November 15, 2019 (SPL set d810a15b-3e10-4f6c-a36e-8ddecbaba9c3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Histamine generic labelers
9Terbutaline generic labelers
HistamineTerbutaline
Labeled forn/an/a
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.947 per tablet 2.5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?