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What the FDA labels say about taking them together

Heparin and ticagrelor

Ticagrelor's FDA label of May 7, 2026 names heparin in its warnings and precautions section; the heparin labels PlainMeds reads (4) do not name ticagrelor.

Check it at the source: the heparin FDA label on DailyMed (effective November 28, 2025, Fresenius Kabi USA, LLC); the ticagrelor FDA label on DailyMed (effective May 7, 2026, AstraZeneca Pharmaceuticals LP).

What does the heparin label say about ticagrelor?

Heparin's label (effective November 28, 2025) and its 3 other brand-application labels do not name ticagrelor in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Heparin Sodium), Fresenius Kabi USA, LLC, effective November 28, 2025 (SPL set d55b4a63-0c04-4874-b74f-9e9b9e8b008c), via openFDA; the full label on DailyMed

What does the ticagrelor label say about heparin?

Ticagrelor label, warnings and precautions

Laboratory Test Interference: False negative platelet functional test results have been reported for Heparin Induced Thrombocytopenia (HIT).

Source: FDA drug label (BRILINTA), AstraZeneca Pharmaceuticals LP, effective May 7, 2026 (SPL set f7b3f443-e83d-4bf2-0e96-023448fed9a8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

18Heparin generic labelers
28Ticagrelor generic labelers
HeparinTicagrelor
Labeled forBlood clots (DVT and PE), Atrial fibrillationHeart attack and coronary artery disease, Stroke prevention
Boxed warningNoYes
Pharmacy cost (NADAC)$1.18 per mL 5,000 unit/mL vial$0.253 per tablet 90 mg tablet
Shortage nowIn shortageNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?