What the FDA labels say about taking them together
Heparin and methoxy polyethylene glycol-epoetin beta
Methoxy polyethylene glycol-epoetin beta's FDA label of August 14, 2026 names heparin in its warnings and precautions section; the heparin labels PlainMeds reads (4) do not name methoxy polyethylene glycol-epoetin beta. The methoxy polyethylene glycol-epoetin beta label: “Patients receiving Mircera may require increased anticoagulation with heparin to prevent clotting of the extracorporeal circuit during hemodialysis.”
Check it at the source: the heparin FDA label on DailyMed (effective November 28, 2025, Fresenius Kabi USA, LLC); the methoxy polyethylene glycol-epoetin beta FDA label on DailyMed (effective August 14, 2026, Vifor (International) Inc.).
What does the heparin label say about methoxy polyethylene glycol-epoetin beta?
Heparin's label (effective November 28, 2025) and its 3 other brand-application labels do not name methoxy polyethylene glycol-epoetin beta in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Heparin Sodium), Fresenius Kabi USA, LLC, effective November 28, 2025 (SPL set d55b4a63-0c04-4874-b74f-9e9b9e8b008c), via openFDA; the full label on DailyMed
What does the methoxy polyethylene glycol-epoetin beta label say about heparin?
Methoxy polyethylene glycol-epoetin beta label, warnings and precautionsPatients receiving Mircera may require increased anticoagulation with heparin to prevent clotting of the extracorporeal circuit during hemodialysis.
Source: FDA drug label (Mircera), BLA125164 (Hoffman-La Roche), as published by Vifor (International) Inc., effective August 14, 2026 (SPL set 22c56f2a-f73c-60e7-e054-00144ff88e88), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Heparin | Methoxy polyethylene glycol-epoetin beta | |
|---|---|---|
| Labeled for | Blood clots (DVT and PE), Atrial fibrillation | Anemia |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.18 per mL 5,000 unit/mL vial | n/a |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once