What the FDA labels say about taking them together
Haloperidol and sotalol
Haloperidol's FDA label (Haloperidol Decanoate) of February 19, 2025 names sotalol in its drug interactions section; the sotalol labels PlainMeds reads (3) do not name haloperidol.
Check it at the source: the haloperidol FDA label on DailyMed (effective April 23, 2026, PD-Rx Pharmaceuticals, Inc.); the sotalol FDA label on DailyMed (effective December 16, 2024, Legacy Pharma USA, Inc.).
What does the haloperidol label say about sotalol?
Haloperidol Decanoate label (Patriot Pharmaceuticals LLC, February 19, 2025), drug interactionsClass 3 antiarrhythmics (e.g., amiodarone, sotalol); and other drugs such as citalopram, erythromycin, levofloxacin, methadone, and ziprasidone.
Source: FDA drug label (Haloperidol Decanoate, NDA018701), Patriot Pharmaceuticals LLC, effective February 19, 2025 (SPL set 9f0f42a8-5f7c-4be7-93ef-3ec225502cc6), via openFDA
Source: FDA drug label (Haloperidol), PD-Rx Pharmaceuticals, Inc., effective April 23, 2026 (SPL set 533b0b4c-cbd6-4ec0-a333-8b04b5b43a1d), via openFDA; the full label on DailyMed
What does the sotalol label say about haloperidol?
Sotalol's label (effective December 16, 2024) and its 2 other brand-application labels do not name haloperidol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (BETAPACE), Legacy Pharma USA, Inc., effective December 16, 2024 (SPL set a6a7702f-36c9-45db-b640-453dc324baee), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Haloperidol | Sotalol | |
|---|---|---|
| Labeled for | Schizophrenia | Atrial fibrillation |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $15.60 per mL 100 mg/mL vial | $0.0707 per tablet 80 mg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once