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What the FDA labels say about taking them together

Haloperidol and quinidine

Haloperidol's FDA label (Haloperidol Decanoate) of February 19, 2025 names quinidine in its drug interactions section, and quinidine's label names haloperidol too. The quinidine label: “Serum levels of haloperidol are increased when quinidine is coadministered.”

Check it at the source: the haloperidol FDA label on DailyMed (effective April 23, 2026, PD-Rx Pharmaceuticals, Inc.); the quinidine FDA label on DailyMed (effective February 1, 2018, Sun Pharmaceutical Industries, Inc.).

What does the haloperidol label say about quinidine?

Haloperidol Decanoate label (Patriot Pharmaceuticals LLC, February 19, 2025), drug interactions

Pharmacodynamic Interactions Since QTc interval-prolongation has been observed during haloperidol treatment, caution is advised when prescribing to a patient with QT-prolongation conditions or to patients receiving medications known to prolong the QTc-interval (see WARNINGS, Cardiovascular Effects ). Examples include (but are not limited to): Class 1A antiarrhythmics (e.g., procainamide, quinidine, disopyramide);

Source: FDA drug label (Haloperidol Decanoate, NDA018701), Patriot Pharmaceuticals LLC, effective February 19, 2025 (SPL set 9f0f42a8-5f7c-4be7-93ef-3ec225502cc6), via openFDA

Source: FDA drug label (Haloperidol), PD-Rx Pharmaceuticals, Inc., effective April 23, 2026 (SPL set 533b0b4c-cbd6-4ec0-a333-8b04b5b43a1d), via openFDA; the full label on DailyMed

What does the quinidine label say about haloperidol?

Quinidine label, drug interactions

Serum levels of haloperidol are increased when quinidine is coadministered.

Source: FDA drug label (Quinidine Gluconate), Sun Pharmaceutical Industries, Inc., effective February 1, 2018 (SPL set 5023f053-fcc4-4c2c-aa59-9ec198ad185e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

41Haloperidol generic labelers
4Quinidine generic labelers
HaloperidolQuinidine
Labeled forSchizophreniaAtrial fibrillation
Boxed warningYesYes
Pharmacy cost (NADAC)$15.60 per mL 100 mg/mL vial$4.92 per tablet 324 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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