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What the FDA labels say about taking them together

Haloperidol and macimorelin

Macimorelin's FDA label of February 18, 2026 names haloperidol in its drug interactions section; the haloperidol labels PlainMeds reads (2) do not name macimorelin. The macimorelin label: “DRUG INTERACTIONS 7.1 Drugs that Prolong QT Interval Co-administration of MACRILEN with drugs that prolong the QT interval may lead to development of torsade de pointes-type ventricular tachycardia.”

Check it at the source: the haloperidol FDA label on DailyMed (effective April 23, 2026, PD-Rx Pharmaceuticals, Inc.); the macimorelin FDA label on DailyMed (effective February 18, 2026, Aeterna Zentaris GmbH).

What does the haloperidol label say about macimorelin?

Haloperidol's label (effective April 23, 2026) and its 1 other brand-application label do not name macimorelin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Haloperidol), PD-Rx Pharmaceuticals, Inc., effective April 23, 2026 (SPL set 533b0b4c-cbd6-4ec0-a333-8b04b5b43a1d), via openFDA; the full label on DailyMed

What does the macimorelin label say about haloperidol?

Macimorelin label, drug interactions

DRUG INTERACTIONS 7.1 Drugs that Prolong QT Interval Co-administration of MACRILEN with drugs that prolong the QT interval (such as antipsychotic medications (e.g., chlorpromazine, haloperidol, thioridazine, ziprasidone), antibiotics (e.g., moxifloxacin), Class 1A (e.g., quinidine, procainamide) and Class III (e.g., amiodarone, sotalol) antiarrhythmic medications or any other medications known to prolong the QT interval) may lead to development of torsade de pointes-type ventricular tachycardia.

Source: FDA drug label (Macrilen), Aeterna Zentaris GmbH, effective February 18, 2026 (SPL set aeb30f1a-4815-47ae-a2cb-b6b4e26372e1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

41Haloperidol generic labelers
0Macimorelin generic labelers
HaloperidolMacimorelin
Labeled forSchizophrenian/a
Boxed warningYesNo
Pharmacy cost (NADAC)$15.60 per mL 100 mg/mL vialn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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