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What the FDA labels say about taking them together

Griseofulvin and norethindrone

Norethindrone's FDA label of January 31, 2026 names griseofulvin in its drug interactions section; the griseofulvin label PlainMeds reads does not name norethindrone. The norethindrone label: “This could result in unintended pregnancy or breakthrough bleeding. Examples include rifampin, barbiturates, phenylbutazone, phenytoin, carbamazepine, felbamate, oxcarbazepine, topiramate, and griseofulvin. b.”

Check it at the source: the griseofulvin FDA label on DailyMed (effective December 10, 2025); the norethindrone FDA label on DailyMed (effective January 31, 2026, Glenmark Pharmaceuticals Inc., USA).

What does the griseofulvin label say about norethindrone?

Griseofulvin's label (effective December 10, 2025) does not name norethindrone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Ultramicrosize Griseofulvin), Chartwell RX, LLC., effective December 10, 2025 (SPL set efb8a660-802c-4ca6-bbff-ad7b48b91aef), via openFDA; the full label on DailyMed

What does the norethindrone label say about griseofulvin?

Norethindrone label, drug interactions

Some drugs or herbal products that may decrease the effectiveness of HCs include efavirenz, phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, rifabutin, rufinamide, aprepitant, and products containing St. John’s wort.

Nora Be label (Teva Pharmaceuticals, Inc., April 2, 2024), drug interactions

This could result in unintended pregnancy or breakthrough bleeding. Examples include rifampin, barbiturates, phenylbutazone, phenytoin, carbamazepine, felbamate, oxcarbazepine, topiramate, and griseofulvin. b.

Source: FDA drug label (Nora Be, NDA017060), Teva Pharmaceuticals, Inc., effective April 2, 2024 (SPL set 426ac898-7745-4645-bf9b-bae319e260e8), via openFDA

Source: FDA drug label (Norethindrone), Glenmark Pharmaceuticals Inc., USA, effective January 31, 2026 (SPL set 0d2f8fea-3675-40d2-afd9-9fcb148dbd4b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

10Griseofulvin generic labelers
18Norethindrone generic labelers
GriseofulvinNorethindrone
Labeled forFungal infectionsBirth control
Boxed warningNoNo
Pharmacy cost (NADAC)$3.74 per tablet 250 mg tablet$0.290 per tablet 5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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