What the FDA labels say about taking them together
Glyburide and miconazole
Glyburide's FDA label of July 1, 2021 names miconazole in its drug interactions section; the miconazole labels PlainMeds reads (2) do not name glyburide. The glyburide label: “A potential interaction between oral miconazole and oral hypoglycemic agents leading to severe hypoglycemia has been reported.”
Check it at the source: the glyburide FDA label on DailyMed (effective July 1, 2021, TEVA Pharmaceuticals USA Inc); the miconazole FDA label on DailyMed (effective July 21, 2026, WALGREEN COMPANY).
What does the glyburide label say about miconazole?
Glyburide label, drug interactionsA potential interaction between oral miconazole and oral hypoglycemic agents leading to severe hypoglycemia has been reported.
Source: FDA drug label (Glyburide), NDA017532 (Sanofi Aventis Us), as published by TEVA Pharmaceuticals USA Inc, effective July 1, 2021 (SPL set 50d16f1d-c814-4411-8749-62561321ecce), via openFDA; the full label on DailyMed
What does the miconazole label say about glyburide?
Miconazole's label (effective July 21, 2026) and its 1 other brand-application label do not name glyburide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Miconazole 3 Walgreen Company), NDA020670 (Medtech Products), as published by WALGREEN COMPANY, effective July 21, 2026 (SPL set 32b373be-9c8e-49b0-a796-8d87f6a20cef), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Glyburide | Miconazole | |
|---|---|---|
| Labeled for | Type 2 diabetes | Fungal infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0643 per tablet 5 mg tablet | $0.120 per gram 2% topical cream |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once