What the FDA labels say about taking them together
Glutamine and valproic acid
Valproic acid's FDA label of January 24, 2025 names glutamine in its warnings and precautions section; the glutamine label PlainMeds reads does not name valproic acid.
Check it at the source: the glutamine FDA label on DailyMed (effective June 20, 2025); the valproic acid FDA label on DailyMed (effective January 24, 2025, PAI Holdings, LLC dba PAI Pharma).
What does the glutamine label say about valproic acid?
Glutamine's label (effective June 20, 2025) does not name valproic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Endari), Emmaus Medical, Inc., effective June 20, 2025 (SPL set d5a783f4-12ef-4326-8faa-40018e45ba3b), via openFDA; the full label on DailyMed
What does the valproic acid label say about glutamine?
Valproic acid label, warnings and precautions1) those with a history of unexplained encephalopathy or coma, encephalopathy associated with a protein load, pregnancy-related or postpartum encephalopathy, unexplained mental retardation, or history of elevated plasma ammonia or glutamine;
Source: FDA drug label (VALPROIC ACID), PAI Holdings, LLC dba PAI Pharma, effective January 24, 2025 (SPL set 7d5cb52e-37dd-4dfa-a6f4-09f9548846c6), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Glutamine | Valproic acid | |
|---|---|---|
| Labeled for | n/a | Seizures and epilepsy, Migraine |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.243 per capsule 250 mg capsule |
| Shortage now | No current entry | Listed; available |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once