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What the FDA labels say about taking them together

Glipizide and terbutaline

Glipizide's FDA label of January 8, 2026 names terbutaline in its drug interactions section; the terbutaline label PlainMeds reads does not name glipizide. The glipizide label: “The following are examples of medication that may reduce the glucose-lowering effect of glipizide extended-release tablets, leading to worsening glycemic control: atypical antipsychotics, corticosteroids, danazol …”

Check it at the source: the glipizide FDA label on DailyMed (effective January 8, 2026, Aurobindo Pharma Limited); the terbutaline FDA label on DailyMed (effective November 15, 2019, ANI Pharmaceuticals, Inc.).

What does the glipizide label say about terbutaline?

Glipizide label, drug interactions

The following are examples of medication that may reduce the glucose-lowering effect of glipizide extended-release tablets, leading to worsening glycemic control: atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), thyroid hormones, phenytoin, nicotinic acid, and calcium channel blocking drugs.

Source: FDA drug label (Glucotrol Xl, NDA020329), Roerig, effective July 21, 2026 (SPL set eed99b60-d043-4249-9b2a-f05e46fb588d), via openFDA

Source: FDA drug label (Glipizide), Aurobindo Pharma Limited, effective January 8, 2026 (SPL set 84794a52-b717-488c-8533-6425c83d405f), via openFDA; the full label on DailyMed

What does the terbutaline label say about glipizide?

Terbutaline's label (effective November 15, 2019) does not name glipizide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Terbutaline Sulfate), NDA017849 (Ani Pharms), as published by ANI Pharmaceuticals, Inc., effective November 15, 2019 (SPL set d810a15b-3e10-4f6c-a36e-8ddecbaba9c3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

31Glipizide generic labelers
9Terbutaline generic labelers
GlipizideTerbutaline
Labeled forType 2 diabetesn/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.0339 per tablet 5 mg tablet$0.947 per tablet 2.5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?