What the FDA labels say about taking them together
Glipizide and miconazole
Glipizide's FDA label of January 8, 2026 names miconazole in its drug interactions section; the miconazole labels PlainMeds reads (2) do not name glipizide. The glipizide label: “Severe hypoglycemia can occur when glipizide and oral miconazole are used concomitantly. Monitor patients closely.”
Check it at the source: the glipizide FDA label on DailyMed (effective January 8, 2026, Aurobindo Pharma Limited); the miconazole FDA label on DailyMed (effective July 21, 2026, WALGREEN COMPANY).
What does the glipizide label say about miconazole?
Glipizide label, drug interactionsSevere hypoglycemia can occur when glipizide and oral miconazole are used concomitantly ( 7.2 , 12.3 ). Monitor patients closely.
Glucotrol Xl label (Roerig, July 21, 2026), drug interactionsDRUG INTERACTIONS ▪ Certain medications may affect glucose metabolism, requiring GLUCOTROL XL dose adjustment and close monitoring of blood glucose ( 7.1 ). ▪ Miconazole: Monitor patients closely.
Source: FDA drug label (Glucotrol Xl, NDA020329), Roerig, effective July 21, 2026 (SPL set eed99b60-d043-4249-9b2a-f05e46fb588d), via openFDA
Source: FDA drug label (Glipizide), Aurobindo Pharma Limited, effective January 8, 2026 (SPL set 84794a52-b717-488c-8533-6425c83d405f), via openFDA; the full label on DailyMed
What does the miconazole label say about glipizide?
Miconazole's label (effective July 21, 2026) and its 1 other brand-application label do not name glipizide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Miconazole 3 Walgreen Company), NDA020670 (Medtech Products), as published by WALGREEN COMPANY, effective July 21, 2026 (SPL set 32b373be-9c8e-49b0-a796-8d87f6a20cef), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Glipizide | Miconazole | |
|---|---|---|
| Labeled for | Type 2 diabetes | Fungal infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0339 per tablet 5 mg tablet | $0.120 per gram 2% topical cream |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once