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What the FDA labels say about taking them together

Gatifloxacin and pimozide

Pimozide's FDA label of August 12, 2026 names gatifloxacin in its drug interactions section; the gatifloxacin label PlainMeds reads does not name pimozide. The pimozide label: “… anti-arrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate …”

Check it at the source: the gatifloxacin FDA label on DailyMed (effective September 8, 2016, Allergan, Inc.); the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC).

What does the gatifloxacin label say about pimozide?

Gatifloxacin's label (effective September 8, 2016) does not name pimozide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (ZYMAXID), NDA022548 (Abbvie), as published by Allergan, Inc., effective September 8, 2016 (SPL set 1160b16c-929a-4e85-9c0b-1d8c96a7678b), via openFDA; the full label on DailyMed

What does the pimozide label say about gatifloxacin?

Pimozide label, drug interactions

Accordingly, pimozide should not be given with dofetilide, sotalol, quinidine, other Class Ia and III anti-arrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol, tacrolimus, ziprasidone, or other drugs that have demonstrated QT prolongation as one of their pharmacodynamic effects.

Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

3Gatifloxacin generic labelers
2Pimozide generic labelers
GatifloxacinPimozide
Labeled forn/an/a
Boxed warningNoNo
Pharmacy cost (NADAC)$8.85 per mL 0.5% eye drops$1.23 per tablet 1 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?