What the FDA labels say about taking them together
Foscarbidopa/foslevodopa and selegiline
Foscarbidopa/foslevodopa's FDA label of March 19, 2026 names selegiline in its drug interactions section; the selegiline labels PlainMeds reads (3) do not name foscarbidopa/foslevodopa. The foscarbidopa/foslevodopa label: “Selective MAO Inhibitors The use of selective MAO-B inhibitors with VYALEV may be associated with orthostatic hypotension.”
Check it at the source: the foscarbidopa/foslevodopa FDA label on DailyMed (effective March 19, 2026, AbbVie Inc.); the selegiline FDA label on DailyMed (effective August 7, 2024, Rising Pharma Holdings, Inc.).
What does the foscarbidopa/foslevodopa label say about selegiline?
Foscarbidopa/foslevodopa label, drug interactionsSelective MAO Inhibitors The use of selective MAO-B inhibitors (e.g., rasagiline and selegiline) with VYALEV may be associated with orthostatic hypotension.
Source: FDA drug label (Vyalev), AbbVie Inc., effective March 19, 2026 (SPL set 28e806e4-951c-40a9-9f0c-d0929caf054c), via openFDA; the full label on DailyMed
What does the selegiline label say about foscarbidopa/foslevodopa?
Selegiline's label (effective August 7, 2024) and its 2 other brand-application labels do not name foscarbidopa/foslevodopa in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Selegiline Hydrochloride), Rising Pharma Holdings, Inc., effective August 7, 2024 (SPL set 23c4481f-d150-40c6-addb-b3e454ca914f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Foscarbidopa/foslevodopa | Selegiline | |
|---|---|---|
| Labeled for | Parkinson's disease | Parkinson's disease, Depression |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.756 per capsule 5 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once