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What the FDA labels say about taking them together

Foscarbidopa/foslevodopa and rasagiline

Foscarbidopa/foslevodopa's FDA label of March 19, 2026 names rasagiline in its drug interactions section; the rasagiline label PlainMeds reads does not name foscarbidopa/foslevodopa. The foscarbidopa/foslevodopa label: “Selective MAO Inhibitors The use of selective MAO-B inhibitors with VYALEV may be associated with orthostatic hypotension.”

Check it at the source: the foscarbidopa/foslevodopa FDA label on DailyMed (effective March 19, 2026, AbbVie Inc.); the rasagiline FDA label on DailyMed (effective June 30, 2020, Teva Pharmaceuticals USA, Inc.).

What does the foscarbidopa/foslevodopa label say about rasagiline?

Foscarbidopa/foslevodopa label, drug interactions

Selective MAO Inhibitors The use of selective MAO-B inhibitors (e.g., rasagiline and selegiline) with VYALEV may be associated with orthostatic hypotension.

Source: FDA drug label (Vyalev), AbbVie Inc., effective March 19, 2026 (SPL set 28e806e4-951c-40a9-9f0c-d0929caf054c), via openFDA; the full label on DailyMed

What does the rasagiline label say about foscarbidopa/foslevodopa?

Rasagiline's label (effective June 30, 2020) does not name foscarbidopa/foslevodopa in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Rasagiline), Teva Pharmaceuticals USA, Inc., effective June 30, 2020 (SPL set e802c83c-e581-4a11-b83d-1df47120078d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Foscarbidopa/foslevodopa generic labelers
14Rasagiline generic labelers
Foscarbidopa/foslevodopaRasagiline
Labeled forParkinson's diseaseParkinson's disease
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.521 per tablet 0.5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?