What the FDA labels say about taking them together
Foscarbidopa/foslevodopa and metoclopramide
Foscarbidopa/foslevodopa's FDA label of March 19, 2026 names metoclopramide in its drug interactions section; the metoclopramide labels PlainMeds reads (2) do not name foscarbidopa/foslevodopa. The foscarbidopa/foslevodopa label: “Antagonists and Isoniazid Dopamine D2 receptor antagonists and isoniazid may reduce the effectiveness of foslevodopa.”
Check it at the source: the foscarbidopa/foslevodopa FDA label on DailyMed (effective March 19, 2026, AbbVie Inc.); the metoclopramide FDA label on DailyMed (effective May 18, 2026, ANI Pharmaceuticals, Inc.).
What does the foscarbidopa/foslevodopa label say about metoclopramide?
Foscarbidopa/foslevodopa label, drug interactionsAntagonists and Isoniazid Dopamine D2 receptor antagonists (e.g., phenothiazines, butyrophenones, risperidone, metoclopramide, papaverine) and isoniazid may reduce the effectiveness of foslevodopa.
Source: FDA drug label (Vyalev), AbbVie Inc., effective March 19, 2026 (SPL set 28e806e4-951c-40a9-9f0c-d0929caf054c), via openFDA; the full label on DailyMed
What does the metoclopramide label say about foscarbidopa/foslevodopa?
Metoclopramide's label (effective May 18, 2026) and its 1 other brand-application label do not name foscarbidopa/foslevodopa in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Metoclopramide), NDA017854 (Ani Pharms), as published by ANI Pharmaceuticals, Inc., effective May 18, 2026 (SPL set 797aad80-0597-42f8-99d5-39de180c3b5a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Foscarbidopa/foslevodopa | Metoclopramide | |
|---|---|---|
| Labeled for | Parkinson's disease | Acid reflux and ulcers, Nausea and vomiting |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.0439 per tablet 10 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once