Skip to main content

What the FDA labels say about taking them together

Foscarbidopa/foslevodopa and isoniazid

Foscarbidopa/foslevodopa's FDA label of March 19, 2026 names isoniazid in its drug interactions section; the isoniazid label PlainMeds reads does not name foscarbidopa/foslevodopa. The foscarbidopa/foslevodopa label: “Dosage adjustment of the antihypertensive drug may be needed. Dopamine D2 receptor antagonists and isoniazid may reduce the effectiveness of VYALEV.”

Check it at the source: the foscarbidopa/foslevodopa FDA label on DailyMed (effective March 19, 2026, AbbVie Inc.); the isoniazid FDA label on DailyMed (effective July 8, 2025, OMNIVIUM PHARMACEUTICALS LLC.).

What does the foscarbidopa/foslevodopa label say about isoniazid?

Foscarbidopa/foslevodopa label, drug interactions

Dosage adjustment of the antihypertensive drug may be needed. ( 7.2 ) Dopamine D2 receptor antagonists and isoniazid may reduce the effectiveness of VYALEV.

Source: FDA drug label (Vyalev), AbbVie Inc., effective March 19, 2026 (SPL set 28e806e4-951c-40a9-9f0c-d0929caf054c), via openFDA; the full label on DailyMed

What does the isoniazid label say about foscarbidopa/foslevodopa?

Isoniazid's label (effective July 8, 2025) does not name foscarbidopa/foslevodopa in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (isoniazid), OMNIVIUM PHARMACEUTICALS LLC., effective July 8, 2025 (SPL set 35400f1d-fd25-4bfa-a382-ac390e21bf2e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Foscarbidopa/foslevodopa generic labelers
14Isoniazid generic labelers
Foscarbidopa/foslevodopaIsoniazid
Labeled forParkinson's diseasen/a
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$3.40 per tablet 300 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?