What the FDA labels say about taking them together
Fosaprepitant and methylprednisolone
Fosaprepitant's FDA label of July 29, 2026 names methylprednisolone in its drug interactions section; the methylprednisolone labels PlainMeds reads (3) do not name fosaprepitant. The fosaprepitant label: “Clinical Impact; Increased methylprednisolone exposure.”
Check it at the source: the fosaprepitant FDA label on DailyMed (effective July 29, 2026, AVYXA Pharma, LLC); the methylprednisolone FDA label on DailyMed (effective June 22, 2026, Mylan Pharmaceuticals Inc.).
What does the fosaprepitant label say about methylprednisolone?
Fosaprepitant label, drug interactionsClinical Impact; Increased methylprednisolone exposure [see ].
Focinvez label (Steriscience Specialties Private Limited, March 30, 2026), drug interactionsClinical Impact; Increased methylprednisolone exposure [see Clinical Pharmacology ()].
Source: FDA drug label (Focinvez, NDA216686), Steriscience Specialties Private Limited, effective March 30, 2026 (SPL set 18a60093-cec8-1b8c-e063-6394a90a8902), via openFDA
Source: FDA drug label (NAVITRUX), AVYXA Pharma, LLC, effective July 29, 2026 (SPL set a41b7c3a-1376-43a7-b5b9-6ba2eba1e169), via openFDA; the full label on DailyMed
What does the methylprednisolone label say about fosaprepitant?
Methylprednisolone's label (effective June 22, 2026) and its 2 other brand-application labels do not name fosaprepitant in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Methylprednisolone), NDA011153 (Pfizer), as published by Mylan Pharmaceuticals Inc., effective June 22, 2026 (SPL set 22dd75d6-f89a-44f7-8ca6-b64c4e9806dd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fosaprepitant | Methylprednisolone | |
|---|---|---|
| Labeled for | n/a | Osteoarthritis, Allergies, Herpes and shingles, Leukemia, lymphoma and myeloma, Crohn's disease and ulcerative colitis, Multiple sclerosis, Asthma, Eczema (atopic dermatitis), Anemia |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.121 per tablet 4 mg tablet |
| Shortage now | A presentation being discontinued | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once