What the FDA labels say about taking them together
Fosamprenavir and raltegravir
Fosamprenavir's FDA label of September 15, 2023 names raltegravir in its drug interactions section; the raltegravir labels PlainMeds reads (2) do not name fosamprenavir.
Check it at the source: the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.); the raltegravir FDA label on DailyMed (effective October 18, 2024, Merck Sharp & Dohme LLC).
What does the fosamprenavir label say about raltegravir?
Fosamprenavir label, drug interactionsConcomitant Drug Class/Drug Name: HIV integrase inhibitor: Raltegravir; Effect on Concentration of Amprenavir or Concomitant Drug: Fosamprenavir: ↓ Amprenavir ↓ Raltegravir Fosamprenavir/ ritonavir: ↓ Amprenavir ↓ Raltegravir; Clinical Comment: Appropriate doses of the combination with respect to safety and efficacy have not been established.
Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed
What does the raltegravir label say about fosamprenavir?
Raltegravir's label (effective October 18, 2024) and its 1 other brand-application label do not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ISENTRESS), Merck Sharp & Dohme LLC, effective October 18, 2024 (SPL set 89a5ec53-d956-4329-8004-0f40f51c88a3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fosamprenavir | Raltegravir | |
|---|---|---|
| Labeled for | HIV | HIV |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $34.54 per tablet 400 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once