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What the FDA labels say about taking them together

Fosamprenavir and quetiapine

Fosamprenavir's FDA label of September 15, 2023 names quetiapine in its drug interactions section; the quetiapine labels PlainMeds reads (2) do not name fosamprenavir. The fosamprenavir label: “Consider alternative antiretroviral therapy to avoid increases in quetiapine drug exposures.”

Check it at the source: the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.); the quetiapine FDA label on DailyMed (effective April 10, 2026, H2-Pharma, LLC).

What does the fosamprenavir label say about quetiapine?

Fosamprenavir label, drug interactions

Consider alternative antiretroviral therapy to avoid increases in quetiapine drug exposures.

Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed

What does the quetiapine label say about fosamprenavir?

Quetiapine's label (effective April 10, 2026) and its 1 other brand-application label do not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (SEROQUEL), NDA020639 (Cheplapharm), as published by H2-Pharma, LLC, effective April 10, 2026 (SPL set 8ae62aaf-f8c5-417f-baac-0098369ca322), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Fosamprenavir generic labelers
48Quetiapine generic labelers
FosamprenavirQuetiapine
Labeled forHIVSchizophrenia, Bipolar disorder, Depression
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.127 per tablet 300 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?