What the FDA labels say about taking them together
Fosamprenavir and pimozide
Fosamprenavir's FDA label of September 15, 2023 names pimozide in its contraindications section; the pimozide label PlainMeds reads does not name fosamprenavir. The fosamprenavir label: “Coadministration is contraindicated due to potential for serious and/or life-threatening reactions such as cardiac arrhythmias.”
Check it at the source: the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.); the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC).
What does the fosamprenavir label say about pimozide?
Fosamprenavir label, contraindicationsRifampin o Antipsychotic: Lurasidone (with ritonavir ), pimozide o Ergot derivatives: Dihydroergotamine, ergonovine, ergotamine, methylergonovine o GI motility agent:
Fosamprenavir label, drug interactionsConcomitant Drug Class/Drug Name: Pimozide; Effect on Concentration of Amprenavir or Concomitant Drug: ↑ Pimozide; Clinical Comment: Coadministration is contraindicated due to potential for serious and/or life-threatening reactions such as cardiac arrhythmias [see ].
Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed
What does the pimozide label say about fosamprenavir?
Pimozide's label (effective August 12, 2026) does not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fosamprenavir | Pimozide | |
|---|---|---|
| Labeled for | HIV | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $1.23 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once