What the FDA labels say about taking them together
Fosamprenavir and lovastatin
Fosamprenavir's FDA label of September 15, 2023 names lovastatin in its contraindications section; the lovastatin label PlainMeds reads does not name fosamprenavir. The fosamprenavir label: “Coadministration with lovastatin or simvastatin is contraindicated due to potential for serious reactions such as risk of myopathy including rhabdomyolysis.”
Check it at the source: the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.); the lovastatin FDA label on DailyMed (effective May 6, 2026, Lupin Pharmaceuticals, Inc.).
What does the fosamprenavir label say about lovastatin?
Fosamprenavir label, contraindicationsLomitapide, lovastatin, simvastatin o Non-nucleoside reverse transcriptase inhibitor: Delavirdine o PDE5 inhibitor:
Fosamprenavir label, drug interactionsConcomitant Drug Class/Drug Name: Lovastatin, simvastatin; Effect on Concentration of Amprenavir or Concomitant Drug: ↑ Lovastatin ↑ Simvastatin; Clinical Comment: Coadministration with lovastatin or simvastatin is contraindicated due to potential for serious reactions such as risk of myopathy including rhabdomyolysis [see ].
Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed
What does the lovastatin label say about fosamprenavir?
Lovastatin's label (effective May 6, 2026) does not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lovastatin), Lupin Pharmaceuticals, Inc., effective May 6, 2026 (SPL set df7ddf4f-d569-431e-81f1-9129d7043150), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fosamprenavir | Lovastatin | |
|---|---|---|
| Labeled for | HIV | High cholesterol, Heart attack and coronary artery disease |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0436 per tablet 20 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once