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What the FDA labels say about taking them together

Follitropin and progesterone

Follitropin's FDA label of May 26, 2026 names progesterone in its warnings and precautions section; the progesterone labels PlainMeds reads (3) do not name follitropin. The follitropin label: “Direct or indirect indices of progesterone production: Urinary or serum luteinizing hormone (LH) rise A rise in basal body temperature Increase in serum progesterone Menstruation following a shift in basal body …”

Check it at the source: the follitropin FDA label on DailyMed (effective May 26, 2026); the progesterone FDA label on DailyMed (effective July 23, 2026, Acertis Pharmaceuticals, LLC).

What does the follitropin label say about progesterone?

Follitropin label, warnings and precautions

Direct or indirect indices of progesterone production are: Urinary or serum luteinizing hormone (LH) rise A rise in basal body temperature Increase in serum progesterone Menstruation following the shift in basal body temperature The following provide sonographic evidence of ovulation:

Source: FDA drug label (Gonal-F Rff Redi-Ject, BLA021684), EMD Serono, Inc., effective April 3, 2025 (SPL set b6d11c45-b502-478e-bb28-2ff596ea259c), via openFDA

Source: FDA drug label (Follistim AQ), Organon LLC, effective May 26, 2026 (SPL set 48489027-e52b-4b10-ae74-4ba03839150c), via openFDA; the full label on DailyMed

What does the progesterone label say about follitropin?

Progesterone's label (effective July 23, 2026) and its 2 other brand-application labels do not name follitropin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Prometrium), Acertis Pharmaceuticals, LLC, effective July 23, 2026 (SPL set 1cf237ff-c4f8-4faa-a7aa-77599c856889), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Follitropin generic labelers
25Progesterone generic labelers
FollitropinProgesterone
Labeled forn/an/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.229 per capsule 100 mg capsule
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?