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What the FDA labels say about taking them together

Fluvoxamine and triazolam

Fluvoxamine's FDA label of June 27, 2026 names triazolam in its warnings and precautions section; the triazolam label PlainMeds reads does not name fluvoxamine. The fluvoxamine label: “Other Potentially Important Drug Interactions Benzodiazepines: Benzodiazepines metabolized by hepatic oxidation should be used with caution because the clearance of these drugs is likely to be reduced by fluvoxamine.”

Check it at the source: the fluvoxamine FDA label on DailyMed (effective June 27, 2026, Zydus Pharmaceuticals USA Inc.); the triazolam FDA label on DailyMed (effective July 10, 2026, Mylan Pharmaceuticals Inc.).

What does the fluvoxamine label say about triazolam?

Fluvoxamine label, warnings and precautions

Other Potentially Important Drug Interactions Benzodiazepines: Benzodiazepines metabolized by hepatic oxidation (e.g., alprazolam, midazolam, triazolam, etc.) should be used with caution because the clearance of these drugs is likely to be reduced by fluvoxamine.

Source: FDA drug label (Fluvoxamine maleate extended-release), Zydus Pharmaceuticals USA Inc., effective June 27, 2026 (SPL set 6c71d4f6-54b5-4d3a-8d2f-b7773c92c32e), via openFDA; the full label on DailyMed

What does the triazolam label say about fluvoxamine?

Triazolam's label (effective July 10, 2026) does not name fluvoxamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Triazolam), NDA017892 (Pfizer), as published by Mylan Pharmaceuticals Inc., effective July 10, 2026 (SPL set 5add318e-11b9-42f8-b052-0d8cebb32fcf), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

16Fluvoxamine generic labelers
7Triazolam generic labelers
FluvoxamineTriazolam
Labeled forn/aInsomnia
Boxed warningYesYes
Pharmacy cost (NADAC)$4.08 per capsule 100 mg capsule$0.308 per tablet 0.25 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?