What the FDA labels say about taking them together
Fluvoxamine and theophylline
Fluvoxamine's FDA label of June 27, 2026 names theophylline in its drug interactions section, and theophylline's label names fluvoxamine too. The fluvoxamine label: “Theophylline: Clearance decreased; reduce theophylline dose by one-third.”
Check it at the source: the fluvoxamine FDA label on DailyMed (effective June 27, 2026, Zydus Pharmaceuticals USA Inc.); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the fluvoxamine label say about theophylline?
Fluvoxamine label, drug interactionsA clinically significant fluvoxamine interaction is possible with drugs having a narrow therapeutic ratio such as pimozide, warfarin, theophylline, certain benzodiazepines, omeprazole, and phenytoin.
Fluvoxamine label, warnings and precautionsTheophylline: Clearance decreased; reduce theophylline dose by one-third ( 5.9 ).
Source: FDA drug label (Fluvoxamine Maleate, NDA021519), ANI Pharmaceuticals, Inc., effective August 4, 2025 (SPL set 7ecd83ec-88f5-4f85-9cc2-9068375d8820), via openFDA
Source: FDA drug label (Fluvoxamine maleate extended-release), Zydus Pharmaceuticals USA Inc., effective June 27, 2026 (SPL set 6c71d4f6-54b5-4d3a-8d2f-b7773c92c32e), via openFDA; the full label on DailyMed
What does the theophylline label say about fluvoxamine?
Theophylline label, drug interactionsFluvoxamine Similar to cimetidine.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluvoxamine | Theophylline | |
|---|---|---|
| Labeled for | n/a | Asthma |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $4.08 per capsule 100 mg capsule | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once