What the FDA labels say about taking them together
Fluvoxamine and pomalidomide
Pomalidomide's FDA label of February 26, 2025 names fluvoxamine in its drug interactions section; the fluvoxamine labels PlainMeds reads (2) do not name pomalidomide. The pomalidomide label: “Drugs That Affect Pomalidomide Plasma Concentrations CYP1A2 inhibitors: In healthy subjects, co-administration of fluvoxamine, a strong CYP1A2 inhibitor, increased C max and AUC of pomalidomide by 24% and 125% …”
Check it at the source: the fluvoxamine FDA label on DailyMed (effective June 27, 2026, Zydus Pharmaceuticals USA Inc.); the pomalidomide FDA label on DailyMed (effective February 26, 2025, Celgene Corporation).
What does the fluvoxamine label say about pomalidomide?
Fluvoxamine's label (effective June 27, 2026) and its 1 other brand-application label do not name pomalidomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Fluvoxamine maleate extended-release), Zydus Pharmaceuticals USA Inc., effective June 27, 2026 (SPL set 6c71d4f6-54b5-4d3a-8d2f-b7773c92c32e), via openFDA; the full label on DailyMed
What does the pomalidomide label say about fluvoxamine?
Pomalidomide label, drug interactionsDrugs That Affect Pomalidomide Plasma Concentrations CYP1A2 inhibitors: In healthy subjects, co-administration of fluvoxamine, a strong CYP1A2 inhibitor, increased C max and AUC of pomalidomide by 24% and 125% respectively [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Pomalyst), NDA204026 (Bristol), as published by Celgene Corporation, effective February 26, 2025 (SPL set 2b25ef01-5c9e-11e1-b86c-0800200c9a66), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluvoxamine | Pomalidomide | |
|---|---|---|
| Labeled for | n/a | Leukemia, lymphoma and myeloma |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $4.08 per capsule 100 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once