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What the FDA labels say about taking them together

Fluvoxamine and pentoxifylline

Pentoxifylline's FDA label of May 15, 2026 names fluvoxamine in its drug interactions section; the fluvoxamine labels PlainMeds reads (2) do not name pentoxifylline. The pentoxifylline label: “Concomitant administration of strong CYP1A2 inhibitors may increase the exposure to pentoxifylline (see ADVERSE REACTIONS).”

Check it at the source: the fluvoxamine FDA label on DailyMed (effective June 27, 2026, Zydus Pharmaceuticals USA Inc.); the pentoxifylline FDA label on DailyMed (effective May 15, 2026, Rising Pharma Holdings, Inc.).

What does the fluvoxamine label say about pentoxifylline?

Fluvoxamine's label (effective June 27, 2026) and its 1 other brand-application label do not name pentoxifylline in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Fluvoxamine maleate extended-release), Zydus Pharmaceuticals USA Inc., effective June 27, 2026 (SPL set 6c71d4f6-54b5-4d3a-8d2f-b7773c92c32e), via openFDA; the full label on DailyMed

What does the pentoxifylline label say about fluvoxamine?

Pentoxifylline label, drug interactions

Concomitant administration of strong CYP1A2 inhibitors (including e.g., ciprofloxacin or fluvoxamine) may increase the exposure to pentoxifylline (see ADVERSE REACTIONS).

Source: FDA drug label (Pentoxifylline), Rising Pharma Holdings, Inc., effective May 15, 2026 (SPL set cd840a2c-2a0e-4b2b-84ff-a0406bb6fa37), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

16Fluvoxamine generic labelers
6Pentoxifylline generic labelers
FluvoxaminePentoxifylline
Labeled forn/an/a
Boxed warningYesNo
Pharmacy cost (NADAC)$4.08 per capsule 100 mg capsule$0.227 per tablet 400 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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