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What the FDA labels say about taking them together

Fluvastatin and voclosporin

Voclosporin's FDA label of August 25, 2026 names fluvastatin in its drug interactions section; the fluvastatin labels PlainMeds reads (2) do not name voclosporin. The voclosporin label: “Monitor for adverse reactions such as myopathy and rhabdomyolysis when OATP1B1/OATP1B3 substrates are used concomitantly with LUPKYNIS and reduce the dosage of these substrates as recommended in their prescribing …”

Check it at the source: the fluvastatin FDA label on DailyMed (effective April 21, 2025, Teva Pharmaceuticals USA, Inc.); the voclosporin FDA label on DailyMed (effective August 25, 2026, Aurinia Pharma U.S., Inc.).

What does the fluvastatin label say about voclosporin?

Fluvastatin's label (effective April 21, 2025) and its 1 other brand-application label do not name voclosporin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Fluvastatin), Teva Pharmaceuticals USA, Inc., effective April 21, 2025 (SPL set aad8b373-0aec-4efb-8e61-3d8114b31127), via openFDA; the full label on DailyMed

What does the voclosporin label say about fluvastatin?

Voclosporin label, drug interactions

Monitor for adverse reactions such as myopathy and rhabdomyolysis when OATP1B1/OATP1B3 substrates (e.g., simvastatin, atorvastatin, pravastatin, rosuvastatin, pitavastatin, fluvastatin) are used concomitantly with LUPKYNIS and reduce the dosage of these substrates as recommended in their prescribing information.

Source: FDA drug label (LUPKYNIS), Aurinia Pharma U.S., Inc., effective August 25, 2026 (SPL set 9f489295-1156-52c7-5fd0-5c4c52f9b813), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Fluvastatin generic labelers
0Voclosporin generic labelers
FluvastatinVoclosporin
Labeled forHigh cholesteroln/a
Boxed warningNoYes
Pharmacy cost (NADAC)$2.88 per tablet 80 mg tabletn/a
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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