What the FDA labels say about taking them together
Fluvastatin and nefazodone
Nefazodone's FDA label of July 31, 2025 names fluvastatin in its drug interactions section; the fluvastatin labels PlainMeds reads (2) do not name nefazodone. The nefazodone label: “… undergo little or no metabolism by the CYP3A4 isozyme, such as pravastatin or fluvastatin, dosage adjustments should not be necessary.”
Check it at the source: the fluvastatin FDA label on DailyMed (effective April 21, 2025, Teva Pharmaceuticals USA, Inc.); the nefazodone FDA label on DailyMed (effective July 31, 2025, Teva Pharmaceuticals USA, Inc.).
What does the fluvastatin label say about nefazodone?
Fluvastatin's label (effective April 21, 2025) and its 1 other brand-application label do not name nefazodone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Fluvastatin), Teva Pharmaceuticals USA, Inc., effective April 21, 2025 (SPL set aad8b373-0aec-4efb-8e61-3d8114b31127), via openFDA; the full label on DailyMed
What does the nefazodone label say about fluvastatin?
Nefazodone label, drug interactionsSince metabolic interactions are unlikely between nefazodone and HMG-CoA reductase inhibitors that undergo little or no metabolism by the CYP3A4 isozyme, such as pravastatin or fluvastatin, dosage adjustments should not be necessary.
Source: FDA drug label (Nefazodone Hydrochloride), Teva Pharmaceuticals USA, Inc., effective July 31, 2025 (SPL set 51ff7db5-aaf9-4c3c-86e6-958ebf16b60f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluvastatin | Nefazodone | |
|---|---|---|
| Labeled for | High cholesterol | Depression |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $2.88 per tablet 80 mg tablet | $1.17 per tablet 100 mg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once