What the FDA labels say about taking them together
Fluticasone and fosamprenavir
Fosamprenavir's FDA label of September 15, 2023 names fluticasone in its drug interactions section; the fluticasone labels PlainMeds reads (4) do not name fosamprenavir. The fosamprenavir label: “Coadministration of fluticasone and fosamprenavir/ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects.”
Check it at the source: the fluticasone FDA label on DailyMed (effective December 19, 2024, Haleon US Holdings LLC); the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.).
What does the fluticasone label say about fosamprenavir?
Fluticasone's label (effective December 19, 2024) and its 3 other brand-application labels do not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (FLONASE ALLERGY RELIEF), Haleon US Holdings LLC, effective December 19, 2024 (SPL set b6134ba0-b70a-4eac-9a82-cef64b242c1d), via openFDA; the full label on DailyMed
What does the fosamprenavir label say about fluticasone?
Fosamprenavir label, drug interactionsCoadministration of fluticasone and fosamprenavir/ritonavir is not recommended unless the potential benefit to the patient outweighs the risk of systemic corticosteroid side effects.
Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluticasone | Fosamprenavir | |
|---|---|---|
| Labeled for | Allergies, Asthma, Eczema (atopic dermatitis) | HIV |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.243 per gram 0.05% cream | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once