What the FDA labels say about taking them together
Fluoxetine/olanzapine and levodopa
Fluoxetine/olanzapine's FDA label of March 31, 2026 names levodopa in its drug interactions section; the levodopa label PlainMeds reads does not name fluoxetine/olanzapine.
Check it at the source: the fluoxetine/olanzapine FDA label on DailyMed (effective March 31, 2026, Teva Pharmaceuticals USA, Inc.); the levodopa FDA label on DailyMed (effective July 20, 2026, Merz Pharmaceuticals, LLC).
What does the fluoxetine/olanzapine label say about levodopa?
Fluoxetine/olanzapine label, drug interactionsEnhanced antihypertensive effect ( 7.7 ) Levodopa and Dopamine Agonists: May antagonize levodopa/dopamine agonists ( 7.7 ) Benzodiazepines:
Source: FDA drug label (Olanzapine and Fluoxetine), Teva Pharmaceuticals USA, Inc., effective March 31, 2026 (SPL set 3c28cf18-01a3-468a-ab3e-8aa82f918251), via openFDA; the full label on DailyMed
What does the levodopa label say about fluoxetine/olanzapine?
Levodopa's label (effective July 20, 2026) does not name fluoxetine/olanzapine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Inbrija), Merz Pharmaceuticals, LLC, effective July 20, 2026 (SPL set 077c0f39-a3a2-4b2b-a184-09131889dcfb), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluoxetine/olanzapine | Levodopa | |
|---|---|---|
| Labeled for | Depression, Bipolar disorder | Parkinson's disease |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $3.44 per unit 3-25 mg | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once