What the FDA labels say about taking them together
Fluconazole and voclosporin
Voclosporin's FDA label of August 25, 2026 names fluconazole in its drug interactions section; the fluconazole labels PlainMeds reads (2) do not name voclosporin. The voclosporin label: “Reduce LUPKYNIS dosage when co-administered with moderate CYP3A4 inhibitors.”
Check it at the source: the fluconazole FDA label on DailyMed (effective April 7, 2026, Zydus Pharmaceuticals (USA) Inc.); the voclosporin FDA label on DailyMed (effective August 25, 2026, Aurinia Pharma U.S., Inc.).
What does the fluconazole label say about voclosporin?
Fluconazole's label (effective April 7, 2026) and its 1 other brand-application label do not name voclosporin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (fluconazole), Zydus Pharmaceuticals (USA) Inc., effective April 7, 2026 (SPL set d1364455-1537-46d4-b093-38cca3be778f), via openFDA; the full label on DailyMed
What does the voclosporin label say about fluconazole?
Voclosporin label, drug interactionsReduce LUPKYNIS dosage when co-administered with moderate CYP3A4 inhibitors (e.g., verapamil, fluconazole, diltiazem) [see Dosage and Administration ( 2.5 ].
Source: FDA drug label (LUPKYNIS), Aurinia Pharma U.S., Inc., effective August 25, 2026 (SPL set 9f489295-1156-52c7-5fd0-5c4c52f9b813), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluconazole | Voclosporin | |
|---|---|---|
| Labeled for | Fungal infections, Urinary tract infections | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.380 per tablet 200 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once