What the FDA labels say about taking them together
Fluconazole and theophylline
Fluconazole's FDA label (Fluconazole) of April 2, 2026 names theophylline in its drug interactions section; the theophylline label PlainMeds reads does not name fluconazole. The fluconazole label: “Drug Interaction Studies.) Theophylline Fluconazole increases the serum concentrations of theophylline.”
Check it at the source: the fluconazole FDA label on DailyMed (effective April 7, 2026, Zydus Pharmaceuticals (USA) Inc.); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the fluconazole label say about theophylline?
Fluconazole label (Mylan Pharmaceuticals Inc., April 2, 2026), drug interactionsDrug Interaction Studies .) Theophylline Fluconazole increases the serum concentrations of theophylline.
Source: FDA drug label (Fluconazole, NDA020090), Mylan Pharmaceuticals Inc., effective April 2, 2026 (SPL set 737e0fac-a2d2-4053-a0d7-edbfb6248f69), via openFDA
Source: FDA drug label (fluconazole), Zydus Pharmaceuticals (USA) Inc., effective April 7, 2026 (SPL set d1364455-1537-46d4-b093-38cca3be778f), via openFDA; the full label on DailyMed
What does the theophylline label say about fluconazole?
Theophylline's label (effective March 10, 2026) does not name fluconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluconazole | Theophylline | |
|---|---|---|
| Labeled for | Fungal infections, Urinary tract infections | Asthma |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.380 per tablet 200 mg tablet | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once