What the FDA labels say about taking them together
Fluconazole and seladelpar lysine
Seladelpar lysine's FDA label of February 3, 2026 names fluconazole in its drug interactions section; the fluconazole labels PlainMeds reads (2) do not name seladelpar lysine. The seladelpar lysine label: “Concomitant Drug or Class: Dual Moderate CYP2C9 and Moderate or Strong CYP3A4 Inhibitors (e.g., fluconazole); Potential Effect on Seladelpar Exposure ↑ = Increase, ↓ = Decrease.: ↑ seladelpar; …”
Check it at the source: the fluconazole FDA label on DailyMed (effective April 7, 2026, Zydus Pharmaceuticals (USA) Inc.); the seladelpar lysine FDA label on DailyMed (effective February 3, 2026, Gilead Sciences, Inc).
What does the fluconazole label say about seladelpar lysine?
Fluconazole's label (effective April 7, 2026) and its 1 other brand-application label do not name seladelpar lysine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (fluconazole), Zydus Pharmaceuticals (USA) Inc., effective April 7, 2026 (SPL set d1364455-1537-46d4-b093-38cca3be778f), via openFDA; the full label on DailyMed
What does the seladelpar lysine label say about fluconazole?
Seladelpar lysine label, drug interactionsConcomitant Drug or Class: Dual Moderate CYP2C9 and Moderate or Strong CYP3A4 Inhibitors (e.g., fluconazole); Potential Effect on Seladelpar Exposure ↑ = Increase, ↓ = Decrease.: ↑ seladelpar; Clinical Intervention: Monitor patients for adverse effects during concomitant use of LIVDELZI with drugs that are dual moderate CYP2C9 and moderate or strong CYP3A4 inhibitors.
Source: FDA drug label (Livdelzi), Gilead Sciences, Inc, effective February 3, 2026 (SPL set 89f79d98-135c-40b2-a585-6996c04e599c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluconazole | Seladelpar lysine | |
|---|---|---|
| Labeled for | Fungal infections, Urinary tract infections | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.380 per tablet 200 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once