What the FDA labels say about taking them together
Fluconazole and ruxolitinib
Ruxolitinib's FDA label of July 20, 2026 names fluconazole in its drug interactions section; the fluconazole labels PlainMeds reads (2) do not name ruxolitinib. The ruxolitinib label: “DRUG INTERACTIONS Fluconazole: Avoid concomitant use with fluconazole doses greater than 200 mg.”
Check it at the source: the fluconazole FDA label on DailyMed (effective April 7, 2026, Zydus Pharmaceuticals (USA) Inc.); the ruxolitinib FDA label on DailyMed (effective July 20, 2026, Incyte Corporation).
What does the fluconazole label say about ruxolitinib?
Fluconazole's label (effective April 7, 2026) and its 1 other brand-application label do not name ruxolitinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (fluconazole), Zydus Pharmaceuticals (USA) Inc., effective April 7, 2026 (SPL set d1364455-1537-46d4-b093-38cca3be778f), via openFDA; the full label on DailyMed
What does the ruxolitinib label say about fluconazole?
Ruxolitinib label, drug interactionsDRUG INTERACTIONS Fluconazole: Avoid concomitant use with fluconazole doses greater than 200 mg.
Source: FDA drug label (JAKAFI), Incyte Corporation, effective July 20, 2026 (SPL set f1c82580-87ae-11e0-bc84-0002a5d5c51b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluconazole | Ruxolitinib | |
|---|---|---|
| Labeled for | Fungal infections, Urinary tract infections | Eczema (atopic dermatitis) |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.380 per tablet 200 mg tablet | $34.01 per gram 1.5% cream |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once